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     <dc:title xml:lang="fr">Infections de prothèses vasculaires extra-cardiaques: une étude observationnelle rétrospective au Centre Hospitalier Universitaire de Rennes</dc:title>
     <dcterms:alternative xml:lang="en">Prosthetic vascular graft infections: an observational retrospective study at the university hospital of Rennes</dcterms:alternative>
     <dc:subject xml:lang="fr">Infections de prothèses vasculaires</dc:subject><dc:subject xml:lang="fr">Staphylococcus sp</dc:subject><dc:subject xml:lang="fr">Antibiothérapie</dc:subject><dc:subject xml:lang="fr">Traitement médico-chirurgical</dc:subject><dc:subject xml:lang="fr">Survie à 1 an</dc:subject>
     <dc:subject xml:lang="en">Prosthetic vascular graft infection</dc:subject><dc:subject xml:lang="en">Staphylococci</dc:subject><dc:subject xml:lang="en">Antimicrobial agents</dc:subject><dc:subject xml:lang="en">Medical and surgical treatment</dc:subject><dc:subject xml:lang="en">One-year cure</dc:subject>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="034007547">Prothèses vasculaires</tef:elementdEntree>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027890163">Staphylococcies</tef:elementdEntree>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027219410">Antibiothérapie</tef:elementdEntree>
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     <dcterms:abstract xml:lang="fr">Les infections de prothèses vasculaires (IPV) sont des complications rares mais graves. Il n’existe, à ce jour, ni définition consensuelle ni recommandations concernant leur prise en charge (PEC). L’objectif de cette étude est de faire un état des lieux du diagnostic et de la PEC des IPV et d’identifier des facteurs pronostics. L’analyse des résultats des 72 patients inclus souligne l’hétérogénéité des symptômes cliniques, de la PEC médico-chirurgicale et de la durée de traitement. Staphylococcus sp est la bactérie prédominante. L’analyse comparative ne retrouve pas de différence en terme de bactériologie ou de survie et aucun facteur de risque de mortalité ne ressort. La mortalité à 1 an liée à l’IPV est de 9,5%. Cette étude confirme l’hétérogénéité clinico-microbiologique des IPV rendant leur diagnostic et leur traitement complexes en l’absence de recommandations. Il est donc nécessaire de réaliser de nouvelles études afin de mieux caractériser ces infections et d’améliorer leur PEC.</dcterms:abstract>
     <dcterms:abstract xml:lang="en">Prosthetic vascular graft infections (PVGI) are uncommon but serious complications. However, there is neither definition nor validated data on the best surgical and medical treatments. The aims of this study are to characterize and compare diagnosis and management of PVGI and to find mortality risk factors. The results analysis shows heterogeneity in clinical presentation, medical and surgical treatment and treatment’s length. Staphylococcus species is the most frequent bacteria documented in PVGI. In term of mortality and bacteriological documentation, there is no difference between subgroups. No mortality risk factors were found. One-year mortality directly due to PVGI is 9,5%. This study confirms the clinical and microbiological heterogeneity of PVGI, whose diagnostic and management are difficult because of the lack of recommendations. Further prospective studies are necessary to establish specific recommendations on the best treatment in order to reduce morbidity and mortality.</dcterms:abstract>
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       <tef:nom>Poinot</tef:nom>
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