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     <dc:title xml:lang="fr">Risque infectieux lors d'un vol spatial habité</dc:title>
     <dcterms:alternative xml:lang="en">Infectious risk during manned spaceflight</dcterms:alternative>
     <dc:subject xml:lang="fr">voyage spatial</dc:subject><dc:subject xml:lang="fr">système immunitaire</dc:subject><dc:subject xml:lang="fr">micropesanteur</dc:subject><dc:subject xml:lang="fr">bactérie</dc:subject><dc:subject xml:lang="fr">écologie</dc:subject><dc:subject xml:lang="fr">adaptation</dc:subject><dc:subject xml:lang="fr">infection</dc:subject>
     <dc:subject xml:lang="en">space travel</dc:subject><dc:subject xml:lang="en">immune system</dc:subject><dc:subject xml:lang="en">microgravity</dc:subject><dc:subject xml:lang="en">bacteria</dc:subject><dc:subject xml:lang="en">ecology</dc:subject><dc:subject xml:lang="en">adaptation</dc:subject><dc:subject xml:lang="en">infection</dc:subject><tef:sujetRameau><tef:vedetteRameauNomCommun>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027255395">Voyages interplanétaires</tef:elementdEntree>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="02933764X">Système immunitaire</tef:elementdEntree>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027809056">Infections </tef:elementdEntree>
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     <dcterms:abstract xml:lang="fr">Implanter des colonies sur la Lune et sur Mars, deux objectifs que les grandes entreprises et institutions du spatial se sont fixés pour les prochaines décennies. Ces voyages de plusieurs mois soulèvent des défis techniques et médicaux majeurs. Plus le voyage est long, plus le risque de blessures est important, et l’inquiétude première réside dans l’apparition d’une infection chez l’un des astronautes. Les conditions extrêmes du vol spatial habité ont des conséquences néfastes sur le système immunitaire. Ces conditions ne préviennent pas la croissance des microorganismes, au contraire la capsule spatiale est un environnement dans lequel les pathogènes opportunistes s’adaptent, développant des caractéristiques qui augmentent leur virulence. Le risque infectieux est donc important lors de ces missions de longue durée et constitue un axe de recherche à part entière. La finalité est d’envisager des nouvelles mesures de protection pour assurer la sécurité des futurs équipages.</dcterms:abstract>
     <dcterms:abstract xml:lang="en">Establishing colonies on the Moon and Mars, two goals that the major space companies and institution have set for the next decades. These trips of several months raise major technical and medical challenges. The longer the trip is, the greater the infectious risk is, and the primary concern lies in an infection development in one of the astronauts. The extreme conditions of manned space flight have adverse consequences on the immune system. These conditions do not prevent the growth of microorganisms, on the contrary, the space capsule is an environment in which opportunistic pathogens adapt, developing characteristics that increase their virulence. The infectious risk is therefore important during these long-term missions and constitutes a research axis in its own right. The goal is to consider new protective measures to ensure the safety of future crews.</dcterms:abstract>
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