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     <dc:title xml:lang="fr">Interactions entre la consommation de cannabis et l’anesthésie locale en odontologie</dc:title>
     <dcterms:alternative xml:lang="en">Interactions between cannabis use and local anesthesia in dentistry</dcterms:alternative>
     <dc:subject xml:lang="fr">Cannabis</dc:subject><dc:subject xml:lang="fr">Anesthésie</dc:subject><dc:subject xml:lang="fr">Odontologie</dc:subject><dc:subject xml:lang="fr">CB1</dc:subject><dc:subject xml:lang="fr">CB2</dc:subject><dc:subject xml:lang="fr">Nociception</dc:subject>
     <dc:subject xml:lang="en">Cannabis</dc:subject><dc:subject xml:lang="en">Anesthetics</dc:subject><dc:subject xml:lang="en">Dentistry</dc:subject><dc:subject xml:lang="en">Dental anesthetic</dc:subject><dc:subject xml:lang="en">Nociception</dc:subject>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027219208">Anesthésie en odontostomatologie</tef:elementdEntree>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027364275">Cannabis </tef:elementdEntree>
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     <dcterms:abstract xml:lang="fr">L’objectif de cet article est d’éclaircir les présomptions faites au sujet de la causalité entre la consommation de cannabis et l’échec de l’anesthésie locale dentaire. La littérature scientifique actuelle démontre l’importance du système endocannabinoïde. Le système endocannabinoïde a des actions périphériques et centrales sur la modulation de la nociception. Cependant les actions exactes des cannabinoïdes exogènes sur le système endocannabinoïde ne sont pas encore bien connues. De cela il est possible de conclure qu’il est trop tôt pour définir l’action du THC sur l’anesthésie dentaire, mais une interaction existe du fait de la présence des récepteurs cannabinoïdes au niveau pulpaire et du système nerveux central. Des études supplémentaires seront nécessaires afin de déterminer la relation précise entre la consommation cannabique et l’anesthésie dentaire.</dcterms:abstract>
     <dcterms:abstract xml:lang="en">The purpose of this article is to clarify the presumptions made about the causality between cannabis use and failure of dental anesthetic. Current scientific literature shows the importance of the endocannabinoid system. The endocannabinoid system has peripheral and central actions on the modulation of nociception. However, the exact actions of exogenous cannabinoids on the endocannabinoid system are not yet well known. From this it is possible to conclude that it is too early to define the action of THC on dental anesthesia, but an interaction exists because of the presence of cannabinoid receptors in the pulp and central nervous system. Further studies will be needed to determine the precise relationship between cannabis consumption and dental anesthesia.</dcterms:abstract>
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