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     <dc:title xml:lang="fr">La consultation chez le médecin généraliste change-t-elle le devenir des patients hospitalisés en réanimation pour syndrome de détresse respiratoire aigüe (SDRA) lié à une pneumopathie aigüe communautaire ?</dc:title>
     <dcterms:alternative xml:lang="en">The impact of general practitioners consultation on ARDS complicating
community acquired pneumonia</dcterms:alternative>
     <dc:subject xml:lang="fr">Pneumopathies</dc:subject><dc:subject xml:lang="fr">Syndrome de détresse respiratoire aigüe</dc:subject><dc:subject xml:lang="fr">soins primaires</dc:subject><dc:subject xml:lang="fr">médecine générale</dc:subject><dc:subject xml:lang="fr">pneumopathie aigue communautaire</dc:subject>
     <dc:subject xml:lang="en">Primary care</dc:subject><dc:subject xml:lang="en">General practicionner</dc:subject><dc:subject xml:lang="en">Community acquired pneumonia</dc:subject><dc:subject xml:lang="en">Acute respiratory distress syndrome</dc:subject>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="177572159">Pneumonie communautaire</tef:elementdEntree>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="030624118">Syndrome de détresse respiratoire aiguë de l'adulte</tef:elementdEntree>
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						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027338215">Médecins généralistes</tef:elementdEntree>
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     <dcterms:abstract xml:lang="fr">Introduction :Les pneumopathies communautaires (PAC) conduisent à de nombreuses consultations chez le médecin généraliste et hospitalisations chaque année. Les PAC sont la plus fréquente cause de syndrome de détresse respiratoire aigüe (SDRA). Le but de cette étude est d’évaluer l’impact de la consultation chez le médecin généraliste sur les SDRA compliquant une PAC. Méthode : Nous avons rétrospectivement colligé les dossiers médicaux de tous les patients admis entre 2006 et 2017 pour SDRA compliquant une PAC. Les patients étaient divisés en deux groupes selon qu’ils aient consulté (GP+) ou pas leur médecin généraliste (GP-) avant l’admission en réanimation. Résultats : 216 patients ont été inclus. Le score SOFA à l’admission était plus élevé dans le groupe GP- comparé au groupe GP+ (respectivement 9.5 (8-13) vs8.5 (7-10 (8-13) ; p=0.003) néanmoins les scores respiratoires SOFA n’étaient pas différents (respectivement 4 (3-4) vs (3-4) ; p=0.31). 71 (70%) GP- et 60 (53%) GP+  présentaient un choc septique à l’admission (p=0.01). L’analyse multivariée trouvait que la consultation chez le médecin généraliste (0,54 [0,29-0,98]; p=0.04) et que la prescription d’antibiotiques (0,46 [0,22-0,99]; p=0.04) étaient associées à une baisse de la mortalité à J 28  Conclusion : La visite chez le médecin généraliste précédent l’admission en réanimation était associée à un meilleur pronostic..
</dcterms:abstract>
     <dcterms:abstract xml:lang="en">INTRODUCTION : Community-acquired pneumonia (CAP) is a potentially severe infection that results in numerous general practitioner (GP) visits and hospital admissions each year. CAP is also the most frequent single cause of acute respiratory distress syndrome (ARDS). Risk factors for development of ARDS in the course of CAP are not clearly defined although prognostic factors associated with mortality have been extensively studied. GP visits, as an early diagnosis and earlier access to antibiotics prescription could significantly affect the course of CAP. The aim of the present study was to evaluate the impact of general practitioners consultation on ARDS complicating CAP admitted to our ICU. METHODS : We retrospectively reviewed the medical records of all patients aged over 18 years admitted between January 1, 2006 and July 31, 2017, for ARDS complicating community acquired pneumonia with a PaO2/FiO2 ratio &lt;150 mmHg after at least 12 h of lung protective mechanical ventilation (MV). Ventilatory modalities for ARDS had been protocolized over the study period as our ICU was recruiting patients for two consecutive multicenter trials (Acurasys and Proseva). Consequently, the protective ventilatory strategy used in these two clinical trials was applied to every patient with ARDS. Patients were divided into two groups according to whether or not they visited a GP before ICU admission. RESULTS : 216 patients were admitted for ARDS complicating CAP. 114 patients (53%) had visited a GP before admission in ICU (GP+) and 102 did not (GP-). Analysis of demographic data, respiratory microbiology patterns, ARDS severity at admission did not show any differences between the two groups. SOFA score at admission was significantly higher in GP- compared to GP+ patients (9,5 (8-13) vs 8,5 (7-10) respectively; p=0.003) although respiratory SOFA scores were not different (4 (3-4) vs 4 (3-4) respectively; p=0.31). 71 (70%) GP- (70%) and 60 (53%) GP+ patients presented septic shock at ICU admission (p=0.01). Multivariate analysis found that GP consultation (0,54 [0,29-0,98]; p=0.04) with antibiotics prescription (0,46 [0,22-0,99]; p=0.04) were associated with decreased mortality at day 28 (figure 1). CONCLUSION : In patients admitted to our ICU for ARDS complicating community acquired pneumonia, GP visits prior to ICU admission was associated with a better outcome. The beneficial effect may be due to earlier antibiotic prescription which could significantly lowered severe infection and septic shock.
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